How to Spend 10 Days in Italy: A Complete Itinerary Guide

Jan 30, 2025

Dreaming of cobblestone streets, authentic pasta, or the sun setting over the canals of Venice? Italy is the perfect destination for you.

Planning any itinerary is surely overwhelming, imagine a 10-day one to Italy. But don’t worry, in this guide, we’ll provide a comprehensive itinerary that takes you through Italy’s most famous cities and regions.

Get ready to explore this fascinating country, and make your trip one to remember!

How to Spend 10 Days in Italy: A Complete Itinerary Guide

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What You Should Know Before Visiting Italy

Before we get to our itinerary, here are some important things to have in mind:

How To Use Trains in Italy

Italy’s train system is easy to use. Buy your tickets online ahead of time and remember to validate them before getting on the train. There are different train classes like “Regionale”, “Intercity” or “Freccia”, and “Freccia” trains tend to be faster. Use apps like Trainline or Trenitalia’s website.

What Is the Best Time to Visit Italian Cities

The best times to visit are in the spring (April-May) and autumn (September-October). These seasons offer pleasant weather, fewer crowds, and the opportunity to enjoy outdoor activities comfortably.

Where to Buy Tickets for Attractions in Italy

Purchase tickets online or in advance to save time and skip long queues, especially in peak season. Trusted sites like Tiqets, GetYourGuide, and the official sites of attractions can be your friends!

How Many Days Do You Need in Italy?

A 10-day Italy trip is enough time to enjoy the country’s culture, food, history, and scenery. You’ll be able to visit major cities and regions like the Amalfi Coast. If you’re looking for a quicker trip or want to focus on specific areas, a 3 or 5-day itinerary might work.

How to Stay Connected with Mobile Data in Italy

With a Yoho Mobile, you can stay always online during your adventure, so, you can be in the loop for reservations, use GPS, be connected on socials, and call when needed. No need to buy a local SIM card every time you travel!

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The best plans for Italy with Yohomobile
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What is the Best Way to Spend 3 Days in Italy?

If you’re only staying for 3 days, make the most of your time. We recommend focusing on one main city like Rome, Milan, or Venice. And be ready to do a lot of walking!

 

Plan the Perfect 10-day Italy Itinerary

Day 1: Ancient Rome

Rome, the Eternal City, is where history comes alive. Get ready to step back in time and explore the iconic landmarks and ancient ruins that make this destination a must-see in your Italy itinerary for 10 days. Tour the

Colosseum and Roman Forum

The Colosseum, is Rome’s most famous ancient amphitheater. Built-in 80 AD, it hosted gladiatorial battles, wild animal hunts, and grand public spectacles. Arriving early, around 8:30 AM, helps you avoid the crowds. A €18 ticket grants access to the Colosseum, Roman Forum, and Palatine Hill, making it a great deal for history lovers.

The Roman Forum, on the other hand, was once the heart of political and social life, and is now a collection of ruins, temples, markets, and basilicas that tell the stories of ancient Rome.

Italy itinerary 10 days: The illuminated Colosseum at twilight in Rome

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Palatine Hill

Palatine Hill, next to the Forum, has great views of the Colosseum and Circus Maximus. Legend says it’s where Romulus and Remus founded Rome. Over time, emperors built grand palaces here, making it a symbol of power and luxury. You can visit with a Colosseum ticket, and it’s best to go early in the morning or late in the afternoon for the best photos.

Piazza Venezia and Capitoline Hill

A short walk from the Colosseum, Piazza Venezia is home to the massive Vittoriano Monument, also called the Altar of the Fatherland. You can climb its terraces for great views of the city. Close by, Capitoline Hill, redesigned by Michelangelo, is a masterpiece example of Renaissance architecture. It houses the Capitoline Museums, filled with Roman sculptures and historical treasures. Tickets cost €15 and visiting in the evening is a great option since the monuments are beautifully lit up, giving them a magical feel.

 

Day 2: Vatican City

On day two of your Italy itinerary, explore Vatican City, a small country inside Rome and the heart of the Catholic Church, where you’ll see incredible art.

St. Peter’s Basilica and the Dome

Begin your journey at St. Peter’s Basilica, the heart of Vatican City and a masterpiece of Baroque architecture. Inside, admire Michelangelo’s Pietà, a breathtaking marble sculpture, and Bernini’s Baldachin, an intricate bronze canopy towering over the altar.

If you’re up for it, climb to the dome for a panoramic view of Rome’s skyline. The basilica is free to enter, but you need a ticket to visit the dome. Remember to follow the dress code: shoulders and knees must be covered.

The Vatican Museums and the Sistine Chapel

A short walk away, the Vatican Museums house one of the world’s most impressive art collections, from classical sculptures to Egyptian artifacts. The €17 ticket is well worth it, giving you access to rooms full of amazing Renaissance art. At the end of the museum tour, you’ll enter the Sistine Chapel, where Michelangelo’s famous frescoes, like The Creation of Adam and The Last Judgment, are on display. Remember that it’s a silent area, and no photos are allowed to protect the artwork.

Aerial view of St. Peter's Square and Vatican City

Photo by Caleb Miller on Unsplash

 

Castel Sant’Angelo and the Vatican Gardens

After crossing the Tiber River, you’ll reach Castel Sant’Angelo. Originally built as Emperor Hadrian’s mausoleum, it later became a papal fortress. Inside, discover its historic chambers, and from the terrace, enjoy amazing views of St. Peter’s Basilica and the river below.

If you seek a peaceful escape, visit the Vatican Gardens with their beautiful fountains and sculptures, which are only accessible through guided tours. These tours also include a visit to the Vatican Museums, a must-see on a 10-day trip to Italy.

The Trevi Fountain

As evening falls, go to Piazza di Trevi to see Rome’s famous fountain. The Trevi Fountain, built in Baroque style, is a symbol of good luck. Tradition says that tossing a coin over your left shoulder with your right hand will ensure you’ll return to Rome.

 

Day 3: Rome’s Landmarks

Rome has much more to offer, so get ready to explore its famous spots on day 3 of your 10-day Italian itinerary.

Piazza Navona and Campo de’ Fiori

Start your day at Piazza Navona, one of Rome’s most beautiful squares, known for its Baroque fountains and lively ambiance. Admire Bernini’s Fontana dei Quattro Fiumi, a sculpture of four major rivers. The Church of Sant’Agnese in Agone and Palazzo Pamphili add to its architectural charm. Visiting in the early morning allows you to soak in the beauty before the crowds arrive.

A short walk away, Campo de’ Fiori a lively market where you can find fresh produce, flowers, and local goods. The square also has a darker past, once being the site of public executions, with a statue of philosopher Giordano Bruno, burned at the stake in 1600, as a reminder.

The Spanish Steps and Villa Borghese

Next, make your way to the Spanish Steps, a grand staircase connecting Piazza di Spagna to Trinità dei Monti. Climb the 135 steps and take in the view from the top, where the Trinità dei Monti church awaits.

At the base, the Fontana della Barcaccia, designed by Pietro Bernini, is a charming landmark. From here, take a walk to Villa Borghese, Rome’s biggest public park, perfect for a relaxing stop. You can visit the Borghese Gallery, which has works by Caravaggio and Bernini, or enjoy the Pincio Terrace with its panoramic views of the city. For a different experience, try renting a bike or a rowboat on the park’s small lake.

Classic stone fountain in a serene park setting

Photo by Gabriella Clare Marino on Unsplash

 

Day 4: Florence’s Renaissance Wonders

On day 4 of your Italy itinerary, we’ll visit the top Renaissance sights in Florence. Take the train to Florence, the heart of the Renaissance, and let’s get started.

Michelangelo’s David at the Accademia Gallery

Start the fourth day of your 10-day Italy itinerary with a visit to the Galleria dell’Accademia, home to Michelangelo’s David, one of the most renowned sculptures in history. Beyond this masterpiece, the museum also has a great collection of Renaissance art, including works by Botticelli and Ghirlandaio. A hidden gem many miss on their itineraries is the historical musical instrument collection with Stradivarius pieces. The museum is open Tuesday to Sunday, from 8:15 AM to 6:50 PM, and closed on Mondays.

Michelangelo's David statue in Florence under a dome

Photo by Mateus Campos Felipe on Unsplash

 

Florence Cathedral (Duomo) and the Baptistery

Next, make your way to Piazza del Duomo, where the Cathedral of Santa Maria del Fiore, known as the Duomo, standing tall in the skyline. Admire its intricate Gothic facade and Brunelleschi’s magnificent dome, an architectural marvel.

You can visit the main floor for free from Monday to Saturday, between 10:15 AM and 4:45 PM, but it’s closed on Sundays. Be sure to check out the Baptistery of San Giovanni, known for its famous Gates of Paradise—bronze doors made by Lorenzo Ghiberti.

Ponte Vecchio and the Uffizi Gallery

In the afternoon, take a walk across Ponte Vecchio, Florence’s famous medieval bridge. It’s lined with historic jewelry shops and art dealers and has been a commercial center for centuries. The Arno River views from here are picture-perfect, especially at sunset. End your day at the Uffizi Gallery, one of the world’s most prestigious art museums, home to famous artworks like Botticelli’s The Birth of Venus, Leonardo da Vinci’s Annunciation, and Michelangelo’s Doni Tondo.

 

Day 5: Pisa and Tuscany Day Trip

Time for a change of scenery on day 5 of your 10-day Italy itinerary with a day trip from Florence to the Tuscan countryside.

Start your trip by taking a train from Florence’s Santa Maria Novella Station to Pisa Centrale, which takes about an hour. Trains run often, making it a convenient and scenic ride. Once you arrive, it’s just a short walk to Piazza dei Miracoli, where you can see some of Pisa’s top attractions. Some agencies, like Viator, offer guided experiences here.

The Leaning Tower of Pisa

No visit to Pisa is complete without seeing the Leaning Tower, Italy’s most recognizable landmark. Take photos from different angles to show off its tilt, and if you’re up for it, climb the 294 steps to the top for amazing views of the city. You need a ticket to enter, so it’s a good idea to book in advance to get the time you want.

Italy itinerary 10 days: Iconic Leaning Tower of Pisa on a bright day

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The Square of Miracles

Beyond the Leaning Tower, Piazza dei Miracoli is a UNESCO World Heritage site filled with architectural gems. You can visit the Pisa Cathedral (Duomo), a beautiful example of Romanesque design, and the Baptistery, known for its remarkable acoustics and detailed marble work. The Campo Santo, a monumental cemetery, is another must-see, famous for its medieval frescoes. While you can access the square for free, you’ll need tickets to enter the individual monuments.

Wine Tasting in the Tuscan Countryside

After exploring Pisa, head into Tuscany’s countryside for a memorable wine-tasting experience. Whether you drive or take a guided tour, you can visit famous areas like Chianti or Val d’Orcia and tour renowned vineyards. Enjoy guided tastings of Chianti Classico, Brunello di Montalcino, and other local favorites, paired with pecorino cheese, cured meats, and fresh Tuscan bread. Many wineries also offer shipping, so you can take a piece of Tuscany home.

Return to Florence

After a day of exploring, head back to Florence. If you took a guided tour, transportation is usually included. Otherwise, you can take an evening train from Pisa Centrale to Florence, arriving just in time for a late dinner. Then, continue your 10-day Italy itinerary the next day.

 

Day 6: Cinque Terre Coastal Beauty

Get your luggage ready to go to Cinque Terre, one of the most iconic landscapes of Italy and the perfect place to fall in love with coastal views and small charming villages.

Riomaggiore and Vernazza

Exploring Cinque Terre means enjoying its beautiful landscapes, and the best way to do this is by hiking the Blue Trail (Sentiero Azzurro). This trail connects all five villages, Riomaggiore, Manarola, Corniglia, Vernazza, and Monterosso al Mare, and offers great views of the coast.

One of the best hikes is from Vernazza to Monterosso al Mare. This 3.8-kilometer trail takes about two hours and passes through vineyards, olive groves, and cliffs with views of the Ligurian Sea. You can also use the Cinque Terre Card for access to paid trails and unlimited train rides between the villages.

Monterosso’s Beaches

After the hike, Monterosso al Mare is the perfect place spot to relax. It has big sandy beaches, unlike the other villages, making it the most beach-friendly destination in Cinque Terre. You can spend the afternoon at Fegina Beach, where you can rent umbrellas and lounge chairs, or swim in the crystal-clear waters. There are cafés nearby where you can grab a drink or snack while enjoying the seaside.

Relaxing beach scene during a glowing sunset

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Local Seafood and Pesto Dishes

A visit to Cinque Terre isn’t complete without trying its authentic flavors. Pesto alla Genovese, made with fresh basil, garlic, pine nuts, and Parmigiano, is a must-try, especially with trofie or trenette pasta. Seafood lovers will certainly enjoy anchovies, calamari, and mussels, all fresh from the Ligurian coast.

For a great meal, check out Ristorante Miky a top choice for its seafood risotto, while L’Ancora della Tortuga for Ligurian dishes with beautiful ocean views.

 

Day 7: Amalfi Coast Adventure

After exploring the beautiful Ligurian coastline, you’ll head south on day 7 to see the amazing Amalfi Coast, a highlight of your 10-day Italy trip.

The Picturesque Streets of Positano

Start your day in Positano, one of Italy’s most photogenic coastal towns. As you walk through its narrow streets, you’ll discover boutique shops, local art galleries, and cozy cafés nestled between pastel-colored buildings.

For a relaxing break, visit Spiaggia Grande, the town’s main beach, where you can admire Positano’s cliffside views while soaking in the morning sun. Have a traditional Italian breakfast with a cornetto and espresso at a café by the sea.

For a more exclusive experience, you can also visit Da Adolfo, a rustic beach restaurant only accessible by boat, offering local dishes and a relaxed vibe.

Amalfi

From Positano, head to the town of Amalfi, which was once a powerful maritime republic. At its heart stands the Duomo di Amalfi, a beautiful cathedral with an Arab-Norman and Gothic styles. Its striped arches, detailed mosaics, and grand staircase make it one of the most impressive cathedrals on the coast. Inside, you can see the painted ceiling, marble columns, and the peaceful Cloister of Paradise with its arches and gardens. If you’re interested in history, the Crypt of St. Andrew holds the relics of the town’s patron saint.

Vibrant houses perched on a rocky coastline

Photo by Tom Podmore on Unsplash

The Amalfi Coast

A great way to experience the Amalfi Coast is by driving along Strada Statale 163 (SS163). This 50-kilometer route goes along cliffs, offering beautiful views of the Tyrrhenian Sea. You’ll pass picturesque villages like Praiano and Ravello, each with its own appeal.

Be sure to stop at viewpoints for amazing photos of the coast. If you’re not comfortable with the narrow, winding roads, you can hire a local driver or join a guided tour to enjoy the scenery without the stress of driving.

 

Day 8: Explore Cinque Terre Villages

On day 8 of your Italy trip, go back to Cinque Terre and explore more of it.

Vernazza’s Harbor

Midday is a great time to visit Vernazza, a beautiful village in Cinque Terre. The harbor, full of colorful buildings and fishing boats, is the heart of this fishing town. You can take a relaxed walk along the waterfront, enjoying the Mediterranean vibe. After that, sit at a restaurant by the harbor and try some fresh seafood. Make sure to have Trofie al Pesto, a traditional Ligurian pasta dish, best paired with a glass of local white wine from nearby vineyards.

Manarola to Corniglia

In the afternoon, put on your hiking shoes and hike from Manarola to Corniglia via Volastra, one of Cinque Terre’s most scenic trails. This 5-kilometer (3-mile) hike passes through olive groves, vineyards, and cliffs with amazing coastal views. The trail is moderately difficult, with some uphill sections and uneven ground, so be sure to wear comfortable shoes and bring water. If you want an easier climb, start in Corniglia, as the incline is gentler from there. This hike is a great stop on your 10-day Italy itinerary by day 8.

Italy itinerary 10 days: Picturesque hillside village surrounded by vineyards

Photo by Josh Hild on Unsplash

 

Day 9: Venice’s Famous Canals

It’s time to visit Venice and experience one of Italy’s most unique sights on day 9 of your trip.

Grand Canal on a Gondola

A trip to Venice isn’t complete without a gondola ride along the Grand Canal. As you glide through the water, you’ll pass by beautiful palaces, stone bridges, and narrow streets that show off the city’s charm. A standard ride lasts about 30 minutes and costs around €80 during the day, with higher prices in the evening.

Gondola floating through a colorful Venetian canal.

Photo by Dmitry Bukhantsov on Unsplash

 

St. Mark’s Basilica in Piazza San Marco

After your gondola ride, head to Piazza San Marco, the heart of Venice. The impressive St. Mark’s Basilica stands in the square, with its golden mosaics, domes, and marble columns. The main basilica is free to enter, but some areas, like the museum and Pala d’Oro, require a ticket.

Doge’s Palace and the Bridge of Sighs

In the afternoon, visit the Doge’s Palace, a symbol of Venetian power and wealth. Walk through its grand halls, filled with Renaissance artwork, and explore the rooms where Venetian rulers once governed.

Don’t miss crossing the Bridge of Sighs, which used to take prisoners from the palace to the dungeons. The palace is typically open from 9:00 AM to 7:00 PM.

 

Day 10: Discover Venice’s Islands

Before leaving Venice, make sure to explore its beautiful islands, it’s a great way to end your 10-day itinerary in Italy.

Murano’s Glass Workshops

Start your final day in Venice with a visit to Murano, the island known for its centuries-old history of glassmaking. Go into one of the famous glass workshops to see skilled artisans create beautiful sculptures, vases, and chandeliers from molten glass.

Make sure to shop at real Murano stores, where each piece comes with a certificate of authenticity. If you’re interested in learning more about the island’s glassmaking tradition, consider taking a guided tour for in-depth insights into the history and artistry behind this craft.

Charming canal lined with small boats and shops

Photo by Balint Miko on Unsplash

 

The Colorful Streets of Burano

Next, take a short boat ride to Burano, one of the most beautiful islands in the Venetian Lagoon. Known for its brightly colored houses, Burano is full of photo opportunities. Stroll through the lovely streets and visit local lace workshops where artisans continue the island’s long tradition of making handmade lace.

Torcello’s Ancient Church

For a peaceful end to your 10-day itinerary to Italy, visit Torcello, the island where Venice’s history began. Unlike its busy neighbors, Torcello is a quiet retreat into the past. Explore the Basilica di Santa Maria Assunta, a Byzantine-era cathedral adorned with some of the most impressive ancient mosaics in Italy.

If you have extra time, visit the Museum of Torcello to learn about this once-thriving island. The calm atmosphere is a great place to reflect on your Italian journey before heading back to Venice, completing your 10-day Italy itinerary.

 

Is Italy Worth Visiting?

Absolutely yes! Italy is a dream destination to visit for history, culture, beautiful views, and great food. From the ancient ruins in Rome to the romantic canals of Venice, there’s so much to see and do.  A 10-day itinerary might not be enough to explore everything, but it’s definitely worth it if you’re planning to visit Italy.

Italy itinerary 10 days: Scenic cliffside village overlooking the sea at dusk

Image by Bela Balla from Pixabay